Moreover, we unveiled that both TGEV and PDCoV infection caused a high-level expression of chemokines mainly associated with T cell immunity, such as CXCL10, CXCL11, and the important costimulatory molecule CD86, but not significant in PEDV-infected enteroids (Figure 9), suggesting that the infection of TGEV and PDCoV may activate a stronger T cell immunity than PEDV. Here, CXCL10 is linked to infection.