IFNA1 and infection: Interestingly, we revealed that although the ability of TGEV and PDCoV to activate the IFN responses was superior to PEDV, both TGEV and PDCoV replicated more robustly than PEDV at the early stage of infection in jejunal enteroids (Figures 1, 5, and 6), suggesting that, unlike PEDV, TGEV and PDCoV may employ some different strategies to evade the IFN responses instead of inhibiting the induction of IFNs.