Results from bulk RNA-seq analysis suggests that pathways like natural killer cell proliferation, negative regulation of interleukin-6 mediated signaling pathway, positive regulation of macrophage differentiation in high FeAS GBM samples; and pathways like positive regulation of glutamate secretion, regulation of glutamate receptor signaling pathway are activated in low FeAS GBM samples. The gene discussed is IL6; the disease is glioblastoma.