PTHLH and osteoporosis: Abaloparatide, which had been developed as a new analog (101) for therapeutic use in osteoporosis, is identical to PTHrP in its first 21 residues, but has 8 residues different from PTHrP between 22 and 34, and is equipotent with PTH peptides in the standard bioassay of total cell cAMP generation in target cells (79, 100, 102).