A previous meta-analysis consisting of 2253 psoriasis patients and 1947 controls highlighted that TNF-α -308G/A polymorphism was significantly associated with decreased risk of psoriasis (GA versus GG: OR 0.67, 95%CI 0.57–0.78, p < 0.001) (Zhuang et al., 2013). The gene discussed is TNF; the disease is psoriasis.