Alleviated the injury of lung function and structure to reduce the progression of COPD. Inhibited inflammatory response in the lung by regulating the expression of IL-1β, IL-6, IL-8, TNF-α, NF-kB, TGF-β1, MMP-9, and TIMP-1. The gene discussed is CXCL8; the disease is chronic obstructive pulmonary disease.