In line with this, a recent study showed that the PG importer PGT (SLCO2A1) is involved in the loading of exogenous PGE2 into intracellular compartments in murine macrophages and human cancer cells resulting in elevated secretion of PGE2 via exocytosis (Shimada et al., 2015; Kasai et al., 2016). The gene discussed is SLCO2A1; the disease is cancer.