ENPP2 and ischemia: In comparison to the control group (48.29 ± 3.94 cells/mm), a significant RGC loss was observed 7 days post ischemia in the I/R group (10.95 ± 2.48 cells/mm; p < 0.001) and in the I/R + ATX-i group (17.61 ± 1.63 cells/mm; p < 0.001).