The I/R (38.44 ± 7.75 cells/mm; p < 0.001) and I/R + ATX-i group (29.04 ± 5.19 cells/mm; p < 0.001) displayed significantly more Iba1+ microglia 7 days after ischemia (control: 5.65 ± 2.29 cells/mm). The gene discussed is ENPP2; the disease is ischemia.