Among them were those encoding apolipoprotein, ATP-binding cassette transporters, nicotinic acetylcholine receptors, adrenoceptors, serotonin receptors, dopamine degradation, dopamine receptors, complement receptors, etc. Similarly, we also compiled a list of 447 MDD-associated genes (Supplementary Table S2; the gene list is referred to as MDDgset, hereafter). The gene discussed is ABCA4; the disease is major depressive disorder.