Accordingly, increased levels of expression of GSK-3β and tyrosine phosphorylation (reflecting GSK-3 activation) were found in postmortem PD brains (Duka et al., 2009; Nagao and Hayashi, 2009; Wills et al., 2010), and both inactive and active forms of GSK-3β were co-localized with α-synuclein (Nagao and Hayashi, 2009). The gene discussed is GSK3B; the disease is Parkinson disease.