NF-κB can promote the release of TNF-α, IL-1β, and type 2 interferon (IFN2), and the synthesis of inducible nitric oxide synthase (iNOS), thus enhancing the phagocytosis and migration of MG and leading to an increase of pathological α-syn and activation of MG. This evidence concerns the gene NFKB1 and myasthenia gravis.