MAP3K3 and Parkinson disease: Moreover, the exogenous delivery of miR-124 can inhibit the expression of mitogen-activated protein kinase 3 (MEKK3) and p-p65 in the SNpc of mice treated with MPTP, and attenuate the activation of MG, thus suggesting that miR-124 may be a potential therapeutic target for regulating PD inflammatory response (Yao et al., 2018).