TGFB1 and prion disease: The results of GSEA analysis showed that bladder cancer, pathways in cancer, focal adhesion, GAP Junction, oocyte meiosis, chemokine signaling pathway, melanoma, WNT signaling pathway, prion disease, TGF-β signaling pathway, Hedgehog signaling pathway, and MAPK signaling pathway were mainly enriched in the high-risk group, while alpha-linolenic acid metabolism, drug metabolism cytochrome P450, oxidative phosphorylation, fatty acid metabolism, peroxisome, and retinol metabolism were mainly enriched in low-risk group (Figure 11).