Immunohistochemical stains for SOX10, S100 protein, P63, cytokeratin5/6, NKX3.1, PSA, alpha-methylacyl-CoA racemase (AMACR), progesterone receptor, STAT6, CD117, DOG1, cyclinD1, smooth muscle actin, desmin, myogenin, HMB45, and claudin-4 (Fig. 4d) were all negative in the tumor cells. This evidence concerns the gene DES and neoplasm.