CENPF and adrenal cortex carcinoma: Then, GSEA enrichment analyses of Biocarta pathway and Hallmark description suggested that cell cycle (NES = 2.03, p = 0; especially G2-phase of mitosis, NES = 1.96, p = 0), G2/M checkpoint (NES = 2.01, p = 0), and E2F targets (NES = 2.04, p = 0) were mostly enriched in ACC patients with CENPFhigh, which implied that CENPF might regulate cell cycle by interacting with E2Fs proteins (Fig. 5b, Additional file 6: Table S6, Additional file 7: Table S7, and Additional file 8: Table S8).