Then, the clinical correlation, prognosis, and potential molecular mechanism of CENPF in ACC patients are mainly analyzed based on the TCGA database; Thus, this study lacks some of our own clinical information, such as tumor subtypes, follow-up data and, expression profiles of CENPF-related genes, which may bring limitations to the clinical application value of CENPF in ACC. Here, CENPF is linked to adrenal cortex carcinoma.