NLRP3 and neoplasm: Given that the hazard ratio of NLRP3 in the prognostic model was 0.68 (P = 0.039), we additionally conducted IHC analyses of NLRP3 staining in samples from 176 patients with HNSCC (Fig. 10B), the results demonstrated that the NLRP3 was significantly correlated with tumor size (P = 0.023).