BCR and acute lymphoblastic leukemia: The typical recurrent translocations occurring in ALL are t(12;21)(p13;q22) causing ETV6/RUNX1, t(1;19)(q23;p13) causing TCF3/PBX1, t(9;22)(q34;q11.2) causing BCR/ABL1, and the most common rearrangement of KMT2A gene, t(4;11)(q21;q23) causing KMT2A/AFF1.