A variety of biomarkers, including carcinoembryonic antigen (CEA), cytokeratin 19 fragments (CYFRA 21–1), carbohydrate antigen (CA)125, CA199 and lactate dehydrogenase (LDH), have been identified to be associated with lung cancer prognosis.11, 12, 13, 14, 15. The gene discussed is CEACAM5; the disease is lung carcinoma.