Morever, α‐synuclein and tubulin compete for the same binding domain on tau protein,50 a microtubule‐associated protein related to the pathophysiology of Alzheimer's disease (AD) and other neurodegenerative disorders that are referred to as tauopathies: by promoting tau phosphorylation, α‐synuclein may inhibit the stabilizing action exerted by tau on microtubules.51, 52. The gene discussed is MAPT; the disease is early-onset autosomal dominant Alzheimer disease.