Since Mdr2−/− mice are a mouse model of inflammation-induced tumour development, and IL-17 has been closely associated with strong induction of regeneration and angiogenesis in the tumour microenvironment [119], we analysed gene expression of cell proliferation markers and known tumour markers of HCC in livers of Mdr2−/− × Tnfr1−/− compared to control mice. The gene discussed is IL17A; the disease is neoplasm.