Similarly, we captured a HER2+ and E/P-cadherin+ tumor cell cluster inside a lymph vessel (SMA+, CD31− and vimentin−) and single E-cadherin+ cells in the surrounding blood vessels (positive for CD31 and vimentin) (Fig. 6f, Supplementary Video 15 and Supplementary Table 4), in the second lymphovascular invasion model. This evidence concerns the gene CDH1 and neoplasm.