Those with elevated ALT were younger (57 years vs 61 years, p ≤ 0.001), with a higher median BMI (29 vs 27, p ≤ 0.001), more T2DM (17% vs 9%, p ≤ 0.001), and a greater proportion met the criteria for the metabolic syndrome (53% vs 38%, p ≤ 0.001) compared to those without ALT elevation. The gene discussed is GPT; the disease is metabolic syndrome.