TP53 and mesothelioma: Analysis of human tumors with endogenous p53 DNA contact, conformational or null mutations (Supplementary Table 1) for upregulated TEAD/YAP transcription revealed high levels in those harboring p53 DNA contact mutations, comparable to H2052 mesothelioma cells with LOF mutations in NF2 and LATS225 (Fig. 1d).