Analysis of human tumors with endogenous p53 DNA contact, conformational or null mutations (Supplementary Table 1) for upregulated TEAD/YAP transcription revealed high levels in those harboring p53 DNA contact mutations, comparable to H2052 mesothelioma cells with LOF mutations in NF2 and LATS225 (Fig. 1d). Here, NF2 is linked to mesothelioma.