Mining of RNAseq data of patient tumor samples with endogenous p53 DNA contact or conformational mutations revealed no statistically significant differences in ROCK1 or ROCK2 expression levels in a TCGA dataset of triple-negative breast cancer (TNBC)s, a subtype with a high frequency of p53 missense mutations49(Supplementary Fig. 13a). Here, ROCK2 is linked to neoplasm.