Despite both factors have been reported to promote neutrophil longevity [43, 44], our data indicate that neither GM-CSF, which was undetectable in apoptotic CM, nor IL-8, which seemed dispensable for neutrophil survival in IL-8 blocking experiments, are responsible for the observed apoptosis delay induced by apoptotic tumour cell-CM. This evidence concerns the gene CXCL8 and neoplasm.