RRAS2 and B-cell chronic lymphocytic leukemia: A comparative RT-qPCR expression analysis of RRAS2 expression in human CLL and in the two mouse models studied here shows that overexpression attained in the mouse systems is within the range of RRAS2 expression levels detected in human leukemias (Fig. 5k), thus reinforcing the idea that the driver role in human CLL is possible.