RRAS2 and B-cell chronic lymphocytic leukemia: At present, we have not elucidated the mechanisms that lead CLL patients that are heterozygous or homozygous for the rs8570 SNP to express more mRNA for RRAS2. However, as this SNP appears at the 3’UTR of the RRAS2 locus, we could hypothesize that higher mRNA in patients bearing the SNP rs8570 is due to resistance to a miRNA.