In contrast, RRAS2 is very frequently overexpressed in the wild type form in different types of cancer, being CLL followed by B-cell non-Hodgkin lymphomas the cancers with the highest expression of mRNA for RRAS2 (Fig. 1c; https://dcc.icgc.org/pcawg). Here, RRAS2 is linked to B-cell non-Hodgkin lymphoma.