IL6 and inflammatory bowel disease: The magnitude of the IL-6 response was significantly greater in the high-intensity intervention, 5 x 4-minute intervals at 80% VO2max interspersed with 3-minute intervals at 50% VO2max, compared to continuous 35-minutes at 50% of VO2max [64], suggesting the intervention implemented by Ploeger et al. [46], with a total of 6-minutes exercising, may not have been of sufficient duration to induce significant change in the abnormal IBD profile [15].