Gzma-/- mice have also been used to show a role for GZMA in inter alia diabetes (Mollah et al., 2017), cancer (Santiago et al., 2020), bacterial infections (García-Laorden et al., 2016; García-Laorden et al., 2017; van den Boogaard et al., 2016), and arthritis (Santiago et al., 2017). This evidence concerns the gene GZMA and bacterial infectious disease.