We performed high‐throughput sequencing of rearranged TCR‐α and TCR‐β genes of Ttet+/Tphe+, Ttet−/Tphe+, and Ttet−/Tphe− CD4+ cells derived either from single cells sorted ex vivo or from TCCs generated in vitro (n = 12 untreated CeD patients). Here, CD4 is linked to cranioectodermal dysplasia.