IL36RN and colonic neoplasm: In contrast to similar downregulation of cytokine and chemokine signaling in Il1f9−/− and Il1f5−/− inflamed colon tissues or colon tumors, the ECM, cell‐matrix interaction and cell adhesion pathways exhibited downregulation and upregulation in Il1f9−/− and Il1f5−/− inflamed colon tissues or colon tumors compared to the respective controls.