Noteworthily, enforced expression of constitutively activated YAP/TAZ in a range of tissue culture and cancer cells regularly induces expression of inflammatory cytokines [83,266–270], which directly highlights that the Hippo pathway is likely a cellular nexus that links epithelial, fibroblasts and endothelial inflammatory responses and proliferation during cancer onset and development [13,261,266]. This evidence concerns the gene YAP1 and cancer.