First, we compared the gene expression levels of CDCAs in TCGA database and found that NUF2, CDCA2, CDCA3, CDCA5, CBX2, and CDCA8 were upregulated in PCa tissues and that the 6 CDCAs were regarded as risk factors for RFS probability in GEPIA. This evidence concerns the gene CDCA5 and posterior cortical atrophy.