ZMPSTE24 and Hutchinson-Gilford progeria syndrome: To our knowledge, only two other studies have reported miRNA expression profiling in a progeroid context, either in mouse embryonic fibroblasts derived from the murine Zmpste24−/− model, phenotypically close to HGPS patients (Xiong et al., 2015; Zhang et al., 2017), or from Zmpste24−/− mouse liver (Mariño et al., 2010; Ugalde et al., 2011).