ARSB and mucopolysaccharidosis type 6: Mucopolysaccharidosis VI (MPS VI, OMIM: 253200) is a rare autosomal recessive lysosomal storage disorder (LSD) caused by mutations in the arylsulfatase B gene (ARSB) located on chromosome 5 (5q13–5q14) (Karageorgos et al., 2007).