We found that six genes [HAMP (encoding hepcidin antimicrobial peptide), SFXN3 (encoding sideroflexin 3), SLC22A17 (encoding solute carrier family 22 member 17), SLC39A14 (encoding solute carrier family 39 member 14), SLC39A8, and SLC48A1] were significantly related to the prognosis of patients with COAD (Supplementary Figure S1). The gene discussed is SFXN3; the disease is colon adenocarcinoma.