As shown in Figure 2G, 37 KO ORTHOLOGY were at different levels between periodontitis and control mice, namely, K00108: choline dehydrogenase [EC:1.1.99.1], K00218: protochlorophyllide reductase [EC:1.3.1.33], K00228: coproporphyrinogen III oxidase [EC:1.3.3.3], etc. The gene discussed is CHDH; the disease is periodontitis.