Therefore, the presence of 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyran-one in P. africana extracts may be responsible for the antiproliferative and proapoptotic effects of the different extracts on PC-3 cancer cells due to its ability to inactivate NF-κB. Additionally, the presence of benzoic acid in P. africana extracts may also be responsible for its anticancer effects. This evidence concerns the gene NFKB1 and cancer.