Lakshmanan et al. suggested that Muc16 contributes to breast cancer progression by increasing cell’s proliferation through interaction with Janus kinase (JAK2) as well as inhibiting cell apoptosis by downregulating of TRAIL (LeBlanc and Ashkenazi, 2003; Lakshmanan et al., 2012). Here, TNFSF10 is linked to breast carcinoma.