This finding adds to that published by Pierce et al. (30) in which T cells from adults compared to children post SARS-CoV-2 infection had more IFN-γ secretion and CD25 expression in response to the spike antigen, and establishes that not only spike but also membrane and nucleocapsid antigens induce a stronger CST response in adults compared to children post infection. The gene discussed is IFNG; the disease is infection.