Analysis of the TCGA dataset showed higher expression levels of ALDH16A1, ALDH3B1, ALDH7A1, ALDH1A2, ALDH3A1 and ALDH1A3 in GBM compared to LGG, while ALDH4A1, ALDH8A1, ALDH1A1, ALDH6A1, ALDH2, ALDH5A1, ALDH1L2 expressions were lower in GBM (Figure 1A). The gene discussed is ALDH6A1; the disease is glioblastoma.