Mechanistically, the effect of the FAK inhibitor on HCC immune infiltration may be due to a decrease in some macrophage recruitment molecules (Ccl2, Flt3lg, Csf1, Csf2) (Soncin et al., 2018; Sterner et al., 2019) and Treg cell recruitment molecules (Ccl20, Cxcl13) (Chen et al., 2017; Ji et al., 2020) in HCC. This evidence concerns the gene CXCL13 and hepatocellular carcinoma.