Barbaloin which is extracted from leaves of Aloe barbadensis Miller, inactivates p38 mitogen-activated protein kinase (MAPK)/HSP27 pathway, induces apoptosis and inhibits growth of human non-small cell lung cancer (NSCLC) cell line, A549 (Zhang et al., 2017). The gene discussed is HSPB1; the disease is non-small cell lung carcinoma.