Pathway analysis in M2-MDMs showed that IFN-λ3 treatment on differentiating macrophages had led to differential expression of genes that were important in several infectious diseases including tuberculosis, salmonellosis, toxoplasmosis, amoebiasis, legionellosis, pertussis, and leishmaniasis (Fig. 6, upper panel). The gene discussed is IFNL3; the disease is pertussis.