Tumour tissues were stained by immunohistochemistry (IHC) for PAX8 to identify HGSC tumour, adenoviral protein, macrophages (F4/80) and natural killer cells (integrin-α2; DX5) (Fig. 6b: representative images taken from a mouse treated with the combination of dl922-947 and carvedilol and culled at time point 3). The gene discussed is PAX8; the disease is neoplasm.