SPI1 and acute myeloid leukemia: For example, TET2 could interact with NANOG in mouse embryonic stem cells4, SPI1/PU.1 in differentiating B-cells5 and monocytes6, early growth response 2 (EGR2) in IL4/GM-CSF-driven human monocyte differentiation7 and Wilms’ tumor suppressor gene1 (WT1) in acute myeloid leukemia cells8,9.