Finally, MIF concentrations in the supernatant of bone marrow aspirates from 10 healthy controls and 35 CMML patients (13 TET2WT, 19 trTET2MUT, and 3 non-trTET2MUT) (Supplementary Table 3) revealed a significant increase of MIF in trTET2MUT CMML samples (Fig. 2g). Here, MIF is linked to chronic myelomonocytic leukemia.