The results revealed that RA patients with A77 1726 > 10 μg/mL were older (p = 0.048), had fewer swollen and tender joints (p < 0.001), had less morning stiffness, pain, and perception of disease severity (p < 0.001), and had lower ESR and CRP (p = 0.036 and p < 0.001, respectively). The gene discussed is ESR1; the disease is rheumatoid arthritis.