Co-immunolabeling for ACE2 and ABCC2 (a.k.a. MRP2, a marker of the biliary pole in hepatocytes) in HCCs, detected ACE2 at the biliary pole and within the lumen of pseudo-glandular tumor structures and in slit-like bile canaliculi (Fig. 2a,b). The gene discussed is ABCC2; the disease is neoplasm.