We found no obvious abnormalities in biochemical indexes of important organs, such as albumin (ALB), alanine aminotransferase (ALT), blood urea nitrogen (BUN), serum creatinine (Scr), amylase (AMY), glucose (Glu), et al. Consequently, our study confirmed that JH-RE-06 holds promise for clinical translation since it not only exerts antitumor effects in lung cancer but also has good safety and no toxicity in vivo. Here, GPT is linked to lung carcinoma.