CD4 and neoplasm: In addition, the immunofluorescence assay (Fig. 5D, E) showed that tumor tissues treated with sh-LINC01123, sh-B7–H3, or the miR-214-3p mimic exhibited increased positive rates of CD4 and CD8 proteins (P < 0.05), and tumor tissues from mice treated with OE-LINC01123 or the miR-214-3p inhibitor had the opposite effect (P < 0.05).