This differs from the pharmacological studies, wherein 5-HT1A receptor stimulation in the postnatal window using the agonist 8-OH-DPAT alone does not modulate anxiety-like behavior, but can increase despair-like behavior in adulthood (Ishikawa and Shiga, 2017), whereas blockade of 5-HT1A receptors in early postnatal life with the selective antagonist WAY 100635 evokes increased anxiety-like behavior (Vinkers et al., 2010; Sarkar et al., 2014). Here, HTR1A is linked to Anxiety.