METTL14 was downregulated in triple-negative breast cancer (TNBC) [118], esophageal cancer (EC) [131], gastric cancer [132], osteosarcoma (OS) [133],Wilms tumor, [134] and oral squamous cell carcinoma (OSCC) [135], and low METTL14 expression was related to poor prognosis. The gene discussed is METTL14; the disease is oral cavity squamous cell carcinoma.