For instance, ALKBH5 was reported to show highly expression in acute myeloid leukemia (AML) and to regulate the stability of AXL mRNA to maintain leukemia stem cell (LSC) function [51], nonetheless, recent reports have shown that ALKBH5 plays an inhibitory role in pancreatic cancer [52]. The gene discussed is AXL; the disease is familial pancreatic carcinoma.