TP53 and B-cell chronic lymphocytic leukemia: In CLL, short telomeres have been associated with markers of inferior prognosis, such as unmutated IGHV genes, increased genomic complexity, 11q deletion/mutated ATM gene, and 17p deletion/mutated TP53 gene [23–30], with short time to first treatment [31] and short overall survival (OS) [17, 27, 32, 33].